Scientific Publications
- Karakavuk M, Can H, Karakavuk T, Gül A, Alak SE, Gül C, Ün C, Gürüz AY, Döşkaya M, Döşkaya AD. Rapid detection of Toxoplasma gondii DNA in cat feces using colorimetric loop-mediated isothermal amplification (LAMP) assays targeting RE and B1 genes. Comp Immunol Microbiol Infect Dis. 2022 Feb;81:101745. doi: 10.1016/j.cimid.2022.101745. Epub 2022 Jan 6. PMID: 35030533.
- Can H, Aksoy Gökmen A, Döşkaya M, Erkunt Alak S, Değirmenci Döşkaya A, Karakavuk M, Köseoğlu AE, Karakavuk T, Gül C, Güvendi M, Gül A, Gürüz AY, Kaya S, Mercier A, Ün C. Development of a new serotyping ELISA for Toxoplasma gondii type II, type III and Africa 1 lineages using in silico peptide discovery methods, well categorized feline and human outbreak serum samples. BMC Infect Dis. 2022 Jan 31;22(1):110. doi: 10.1186/s12879-022-07088-w. PMID: 35100997; PMCID: PMC8802539.
- Akıl M, Aykur M, Karakavuk M, Can H, Döşkaya M. Construction of a multiepitope vaccine candidate against Fasciola hepatica: an in silico design using various immunogenic excretory/secretory antigens. Expert Rev Vaccines. 2021 Nov 1:1-14. doi: 10.1080/14760584.2022.1996233. Epub ahead of print. PMID: 34666598.
- Muz D, Can H, Karakavuk M, Döşkaya M, Özdemir HG, Değirmenci Döşkaya A, Atalay Şahar E, Pektaş B, Karakuş M, Töz S, Özbel Y, Gürüz AY, Muz MN. The molecular and serological investigation of Feline immunodeficiency virus and Feline leukemia virus in stray cats of Western Turkey. Comp Immunol Microbiol Infect Dis. 2021 Oct;78:101688. doi: 10.1016/j.cimid.2021.101688. Epub 2021 Jun 29. PMID: 34229197.
- Karakavuk M, Can H, Döşkaya M, Karakavuk T, Erkunt-Alak S, Köseoğlu AE, Gül A, Ün C, Gürüz Y, Değirmenci-Döşkaya A. Cryptosporidiosis outbreak on a dairy farm: Detection of Cryptosporidium parvum as a causative agent in the water source. Pol J Vet Sci. 2021 Sep;24(3):323-333. doi: 10.24425/pjvs.2021.137669. PMID: 34730310.
- Karabey M, Can H, Öner TÖ, Döşkaya M, Alak SE, Döşkaya AD, Karakavuk M, Köseoğlu AE, Ün C, Gürüz AY, Alacacıoğlu A, Pektaş B, Gül A, Kaya S, Gökmen AA. Cryptosporidium spp. during chemotherapy: a cross-sectional study of 94 patients with malignant solid tumor. Ann Saudi Med. 2021 Sep-Oct;41(5):293-298. doi: 10.5144/0256-4947.2021.293. Epub 2021 Oct 7. PMID: 34618605; PMCID: PMC8497003.
- Karakavuk M, Can H, Gül A, Döşkaya AD, Alak SE, Ün C, Gürüz AY, Döşkaya M. GRA8 DNA vaccine formulations protect against chronic toxoplasmosis. Microb Pathog. 2021 Sep;158:105016. doi: 10.1016/j.micpath.2021.105016. Epub 2021 Jun 7. PMID: 34098019.
- Can H, Köseoğlu AE, Erkunt Alak S, Güvendi M, Ün C, Karakavuk M, Değirmenci Döşkaya A, Aykur M, Aksoy Gökmen A, Gürüz AY, Döşkaya M. Molecular prevalence and subtyping of Blastocystis sp. isolates in stray cats of İzmir, Turkey: First report of "ST4 allele 42" in cats. Pol J Vet Sci. 2021 Jun;24(2):217-223. doi: 10.24425/pjvs.2021.137656. PMID: 34250772.
- Köseoğlu AE, Can H, Güvendi M, Erkunt Alak S, Kandemir Ç, Taşkın T, Demir S, Akgül G, Değirmenci Döşkaya A, Karakavuk M, Döşkaya M, Gürüz AY, Ün C. Molecular investigation of bacterial and protozoal pathogens in ticks collected from different hosts in Turkey. Parasit Vectors. 2021 May 20;14(1):270. doi: 10.1186/s13071-021-04779-2. PMID: 34016174; PMCID: PMC8138928.
- Gülce-İz S, Elaldı N, Can H, Şahar EA, Karakavuk M, Gül A, Kumoğlu GÖ, Döşkaya AD, Gürüz AY, Özdarendeli A, Felgner PL, Davies H, Döşkaya M. (2021). Development of a novel recombinant ELISA for the detection of Crimean-Congo hemorrhagic fever virus IgG antibodies. Sci Rep. 2021 Mar 15;11(1):5936.
- Can H, Erkunt Alak S, Köseoğlu AE, Şahar U, Bostanbaş B, Baydarlı S, Döşkaya M, Ün C. (2021). Molecular characterization of cytidine monophospho-N-acetylneuraminic acid hydroxylase (CMAH) gene and frequency of blood types in stray cats of İzmir, Turkey. BMC Genomics. 2021 Apr 19;22(1):282.
- Karakavuk M, Can H, Selim N, Yeşilsiraz B, Atlı E, Atalay Şahar E, Demir F, Gül A, Özdemir HG, Alan N, Yalçın M, Özkurt O, Aras M, Çelik T, Can Ş, Değirmenci Döşkaya A, Gürüz AY, Döşkaya M. (2020). Investigation of the role of stray cats for transmission of toxoplasmosis to humans and animals living in İzmir, Turkey. J Infect Dev Ctries. 2021 Jan 31;15(1):155-162.
- Aykur M, Karakavuk E, Karakavuk M, Akıl M, Can H, Döşkaya M, Gürüz AY, Dağcı H (2020). Inhibitory effect of Tunceli garlic (Allium tuncelianum) on blastocystis subtype 3 grown in vitro. Expert Opinion on Orphan Drugs, 1-8.
- Can H, Köseoğlu AE, Erkunt Alak S, Güvendi M, Döşkaya M, Karakavuk M, Gürüz AY, Ün C. In silico discovery of antigenic proteins and epitopes of SARS-CoV-2 for the development of a vaccine or a diagnostic approach for COVID-19. Sci Rep. 2020 Dec 28;10(1):22387.
- Atalay Şahar E, Döşkaya M, Karakavuk M, Can H, Gül A, Gürüz AY, Değirmenci Döşkaya A, Yeniay L. Toxoplasma gondii destroys Her2/Neu-expressing mammary cancer cells in vitro using a continuous feed medium approach. J Infect Dev Ctries. 2020 Oct 31;14(10):1204-1209.
- Şahar EA, Can H, İz SG, Döşkaya AD, Kalantari-Dehaghi M, Deveci R, Gürüz AY, Döşkaya M. (2020). Development of a hexavalent recombinant protein vaccine adjuvanted with Montanide ISA 50 V and determination of its protective efficacy against acute toxoplasmosis.BMC Infect Dis. 2020 Jul 10;20(1):493.
- Erkunt Alak S, Köseoğlu AE, Kandemir Ç, Taşkın T, Demir S, Döşkaya M, Ün C, Can H. (2020). High frequency of knockdown resistance mutations in the para gene of cat flea (Ctenocephalides felis) samples collected from goats. Parasitol Res. 2020 Jul;119(7):2067-2073.
- Sürgeç E, Can H, Döşkaya M, Karakavuk M, Atalay Şahar E, Değirmenci Döşkaya A, Pullukçu H, Taşbakan M, Sezai Taşbakan M, Akyol D, Yargucu Zihni F, Ün C, Yüksel Gürüz A, Demir S. (2020). Genotyping of Pneumocystis jirovecii isolates obtained from clinical samples by multilocus sequencing: a molecular epidemiology study conducted in Turkey. Arch Microbiol. 2020 Sep;202(7):1647-1652.
- Can H, Erkunt Alak S, Köseoğlu AE, Döşkaya M, Ün C. (2020). Do Toxoplasma gondii apicoplast proteins have antigenic potential? An in silico study. Comput Biol Chem; 84:107158. doi: 10.1016/j.compbiolchem.2019.107158.
- Döşkaya M, Pullukçu H, Karakavuk M, Şahar EA, Taşbakan MS, Taşbakan MI, Yılmaz M, Can H, Döşkaya AD, Gürüz AY. (2019). Comparison of an in house and a commercial real-time polymerase chain reaction targeting Toxoplasma gondii RE gene using various samples collected from patients in Turkey. BMC Infect Dis. 19(1):1042. doi: 10.1186/s12879-019-4666-z.
- Örs Kumoğlu G, Döşkaya M, Gulce Iz S. (2019). The biomarker features of miR-145-3p determined via meta-analysis validated by qRT-PCR in metastatic cancer cell lines. Gene. 710:341-353. doi: 10.1016/j.gene.2019.05.038.
- Sağlam Metiner P., Can H, Ayyıldız Tamiş D., Karakavuk M., Kımız Geboloğlu I., Gülçe İz S., Atalay Şahar E., Değirmenci Döşkaya A., Gürüz Y., Deliloğlu Gürhan S.İ., Döşkaya M. (2019). The use of Toxoplasma gondii tachyzoites produced in HeLa cells adhered to Cytodex 1 microcarriers as antigen in serological assays: an application of microcarrier technology. Cytotechnology. doi: 10.1007/s10616-018-0269-6.
- Korkmaz Ekren P., Töreyin ZN, Nahid P., Doskaya M., Caner A., Turgay N., Zeytinoglu A., Toz S., Bacakoglu F., Guruz Y., Erensoy S. (2018). The association between Cytomegalovirus co-infection with Pneumocystis pneumonia and mortality in immunocompromised non-HIV patients. Clin Respir J. 12(11):2590-2597. doi: 10.1111/crj.12961.
- Can H., Kayalar H., Bozkurt B., Can Ş., Döşkaya M., Töz S. (2018). In vitro anti-leishmanial activity of Sarcopoterium spinosum against Leishmania tropica. Ankara Üniv Vet Fak Derg, 65: 373-377.
- Döşkaya M., Liang L., Jain A., Can H., Gülçe İz S., Felgner P.L., Değirmenci Döşkaya A., Davies D.H., Gürüz A.Y. (2018). Discovery of new Toxoplasma gondii antigenic proteins using a high throughput protein microarray approach screening sera of murine model infected orally with oocysts and tissue cysts. Parasit Vectors. 11(1):393. doi: 10.1186/s13071-018-2934-1.
- Karakavuk M., Aldemir D., Mercier A., Atalay Şahar E., Can H., Murat J.B., Döndüren Ö., Can Ş., Özdemir H.G., Değirmenci Döşkaya A., Pektaş B., Dardé M.L., Gürüz A.Y., Döşkaya M. (2018). Prevalence of toxoplasmosis and genetic characterization of Toxoplasma gondii strains isolated in wild birds of prey and their relation with previously isolated strains from Turkey. PLoS One, 13(4):e0196159. doi: 10.1371/journal.pone.0196159. eCollection 2018.
- Zorbozan O., Pullukçu H., Atalay Şahar E., Karakavuk M., Can H., Tunali V., Döşkaya M., Turgay N., Töz S., Özbilgin A. (2017). The importance of the contribution of rapid test, serological and molecular methods in the diagnosis of two imported malaria cases with atypical microscopy. Mikrobiyol Bul, 51(4):396-403. doi: 10.5578/mb.61822.
- Karakavuk M., Aykur M., Şahar E.A., Karakuş M., Aldemir D., Döndüren Ö., Özdemir H.G., Can H., Gürüz A.Y., Dağcı H., Döşkaya M. (2017). First time identification of Acanthamoeba genotypes in the cornea samples of wild birds; Is Acanthamoeba keratitis making the predatory birds a target?, Exp Parasitol, 183:137-142. doi: 10.1016/j.exppara.2017.08.007.
- Kıvrak E.E., Atalay Şahar E., Can H., Döşkaya M., Yılmaz M., Pullukçu H., Caner A., Töz H., Gürüz Y., Işıkgöz M. (2017). Screening of immunocompromised patients under risk of strongyloidiasis in western Turkey using ELISA and real - time PCR. Turk J Med Sci, DOI: 10.3906/sag-1605-19
- Anıl M., Gülçe İz S., Metıner P.S., Sahar E.A., Can H., Zekioğlu O., et al., "Tumour forming efficiencies of TUBO cell line expressing Her2 in two different mice strains with Matrigel matrix to develop animal models for novel immunotherapies", EUROPEAN JOURNAL OF CANCER, vol.55, pp.S12-S12, 2016
- Can H., Döşkaya M., Özdemir H.G., Şahar E.A., Karakavuk M., Pektaş B., Karakuş M., Töz S., Caner A., Değirmenci Döşkaya A., Gülce İz S., Özbel Y., Gürüz Y. (2016). Seroprevalence of Leishmania infection and molecular detection of Leishmania tropica and Leishmania infantum in stray cats of İzmir, Turkey. Exp Parasitol, 167:109-14. DOI: 10.1016/j.exppara.2016.05.011.
- Can H., İnceboz T., Caner A., Atalay Şahar E., Karakavuk M., Döşkaya M., Çelebi F., Döşkaya A.D., Gülçe İz S., Gürüz Y., Korkmaz M. (2016). Detection of Echinococcus granulosus and Echinococcus multilocularis in Cyst Samples Using a Novel Single Tube Multiplex Real Time Polymerase Chain Reaction. Mikrobiyol Bul, 50(2): 266-267. DOI: 10.5578/mb.21005.
- Can H., Atalay Şahar E., Döşkaya M., Özdemir H.G., Caner A., Döşkaya A.D., Gürüz Y., Ün C. (2016). Analysis of Cytidine Monophospho-N-Acetylneuraminic Acid Hydroxylase (CMAH) Gene Related to Neonatal Isoerythrolysis in Stray Cats of Izmir, Turkey. Kafkas Univ Vet Fak Derg, 22 (3): 355-359, DOI: 10.9775/kvfd.2015.14637.
- Gedik Y., İz S.G., Can H., Değirmenci Döşkaya A., Gürhan İ.D., Gürüz Y., Döşkaya M. (2016). Immunogenic multistage recombinant protein vaccine confers partial protection against experimental toxoplasmosis mimicking natural infection in murine model. Trials in Vaccinology, 5: 15-23. DOI:10.1016/j.trivac.2015.11.002.
- Değirmenci Döşkaya A., Döşkaya M., Caner A., Gül K., Nergiz Ş. Can H., Gürüz Y. (2015). Preliminary analysis of Plasmodium vivax genotypes isolated in southeastern Turkey. Acta Parasitologica, 60 (2): 244-247. DOI: 10.1515/ap-2015-0034.
- Felgner J., Juarez S., Hung C., Liang L., Jain A., Döskaya M., Felgner P.L., Caner A., Gürüz Y., Davies D.H. (2015). Identification of Toxoplasma gondii antigens associated with different types of infection by serum antibody profiling. Parasitology, 142(6):827-38.
- İz S.G., Döşkaya M., Caner A., Değirmenci Döşkaya A., Rodriguez F., Gürüz Y., Gürhan SID. (2014). A novel dual promoter DNA vaccine induces CD8+ response against Toxoplasma gondii sporozoite specific surface protein “SporoSAG” through non-apoptotic cells. Trials in Vaccinology, 3: 81–88. DOI: 10.1017/S0031182014001978. Epub 2015 Jan 14.
- Döşkaya M., Caner A., Can H., Gülçe İz S., Gedik Y., Değirmenci Döşkaya A., Kalantari-Dehaghi M., Gürüz Y. (2014). Diagnostic value of a Rec-ELISA using Toxoplasma gondii recombinant SporoSAG, BAG1, and GRA1 proteins in murine models infected orally with tissue cysts and oocysts. PLoS One, 9(9):e108329. DOI: 10.1371/journal.pone.0108329. eCollection 2014.
- Can H., Döşkaya M., Ajzenberg D., Özdemir H.G., Caner A., İz S.G., Döşkaya A.D., Atalay E., Çetinkaya Ç., Ürgen S., Karaçalı S., Ün C., Dardé M.L., Gürüz Y. (2014). Genetic characterization of Toxoplasma gondii isolates and toxoplasmosis seroprevalence in stray cats of İzmir, Turkey. PLoS One, 9(8):e104930. DOI: 10.1371/journal.pone.0104930. eCollection 2014.
- Döşkaya M., Caner A., Ajzenberg D., Değirmenci A., Dardé M.L., Can H., Erdoğan D.D., Korkmaz M., Uner A., Güngör C., Altıntaş K., Gürüz Y. (2013). Isolation of Toxoplasma gondii strains similar to Africa 1 genotype in Turkey. Parasitol Int, 62(5):471-4. DOI: 10.1016/j.parint.2013.06.008. Epub 2013 Jun 28.
- Gülçe İz S, Döşkaya M., Borrego B, Rodriguez F, Gürüz Y, Gürhan ID. (2013). Co-expression of the Bcl-xL antiapoptotic protein enhances the induction of Th1-like immune responses in mice immunized with DNA vaccines encoding FMDV B and T cell epitopes. Vet Res Commun, 37(3):187-96. DOI: 10.1007/s11259-013-9560-3. Epub 2013 Mar 13.
- Polat C., İz S.G., Döşkaya M., Can H., Caner A., Değirmenci A., Balcan E., Gürüz Y. (2013). Comparison of Immune Responses Elicited by Adjuvanted Tachyzoite Lysate Vaccines Developed from Two Different Toxoplasma gondii Strains Isolated in Turkey. Mikrobiyol Bul, 47(1): 122-134.DOI: 10.5578/mb.4348.
- Caner A, Dönmez A, Döşkaya M, Değirmenci A, Tombuloğlu M, Cağirgan S, Guy E, Francis J, Soyer NA, Gürüz Y. (2012). Determining Toxoplasma high-risk autologous and allogeneic hematopoietic stem cell transplantation patients by systematic pre-transplant PCR screening of stem cell originated buffy coat. Parasitol Int, 61(4):565-71. DOI: 10.1016/j.parint.2012.05.005.
- Değirmenci A, Döşkaya M, Caner A, Nergis S, Gül K, Aydınok Y, Ertop T, Aksoy N, Korkmaz M, Alkan MZ, Üner A, Gürüz Y. (2012). Action plan to regain unnecessary deferred blood donors due to malaria risk in Turkey. Transfus Apher Sci, 46(3):269-75. DOI: 10.1016/j.transci.2012.03.008. Epub 2012 Mar 29.
- Liang L, Döskaya M, Juarez S, Caner A, Jasinskas A, Tan X, Hajagos BE, Bradley PJ, Korkmaz M, Güruz Y, Felgner P, Davies DH. (2011). Identification of potential serodiagnostic and subunit vaccine antigens by antibody profiling of toxoplasmosis cases in Turkey. Mol Cell Proteomics, 10(7):M110.006916. DOI: 10.1074/mcp.M110.006916. Epub 2011 Apr 21.
- Döşkaya M, Caner A, Degirmenci A, Wengenack NL, Yolasigmaz A, Turgay N, Ozensoy Toz S, Guruz Y. (2011). Degree and frequency of inhibition in a routine Real Time PCR detecting Pneumocystis jirovecii for the diagnosis of Pneumocystis pneumonia in Turkey. J Med Microbiol, 60(Pt 7):937-44. DOI: 10.1099/jmm.0.030775-0. Epub 2011 Apr 1.
- Değirmenci, A., Döşkaya, M., Caner, A., Çiçek, C., Korkmaz, M., Gürüz, Y, Üner A., (2011). Toxoplasma gondii RH Ankara: Production of evolving tachyzoites using a novel cell culture method. Exp Parasitol. 128(1):1-8. DOI: 10.1016/j.exppara.2011.01.019. Epub 2011 Feb 4.
- Kılınç O., Döşkaya M., Şakar A., Yorgancıoğlu A., Halilçolar H., Caner A., Gürüz Y. (2009). Three atypical pulmonary hydatidosis lesions mimicking bronchial cancer from Turkey. New Microbiologica, 32(2):229-33.
- Döşkaya, M., Caner, A., Değirmenci, A., Jurnak, F., Gürüz, Y. (2009). Investigation of folding of purified recombinant GRA1 protein using web based protein disorder servers and trypsin digestion. Protein and Peptide Letters. 16(7):834-41. DOI: 10.2174/092986609788681832
- Caner, A., Döşkaya, M., Karasu, Z., Değirmenci, A., Guy, E., Kiliç, M., Zeytunlu, M., Francis, J., Bozoklar, A., Gürüz, Y. (2008). Incidence and diagnosis of active toxoplasma infection among liver transplant recipients in Western Turkey. Liver Transpl, 14(10):1526-32. DOI: 10.1002/lt.21558.
- Caner, A., Döşkaya, M., Değirmenci, A., Can, H., Baykan, S., Uner, A., Başdemir, G., Zeybek, U., Gürüz, Y. (2008). Comparison of the effects of Artemisia vulgaris and Artemisia absinthium growing in western Anatolia against trichinellosis (Trichinella spiralis) in rats. Exp Parasitol, 119: 173-179. DOI: 10.1016/j.exppara.2008.01.012. Epub 2008 Feb 5.
- Döşkaya, M., Kalantari-Dehaghi, M., Walsh, C.M., Hiszczynska-Sawicka, E., Davies, D.H., Felgner, P.L., Larsen, L.S., Lathrop, R.H., Hatfield, G.W., Schulz, J.R., Gürüz, Y., Jurnak, F. (2007). GRA1 protein vaccine confers better immune response compared to codon-optimized GRA1 DNA vaccine. Vaccine, 25(10):1824-37. DOI:10.1016/j.vaccine.2006.10.060.
- Döşkaya, M., Değirmenci, A., Çiçek, C., Ak, M., Korkmaz, M., Gürüz, Y., Üner, A. (2006). Behaviour of Toxoplasma gondii RH Ankara strain tachyzoites during continuous production in various cell lines. Parasitology, 132:315-319. DOI: 10.1017/S0031182005009078.